Founded in 2016, A-Mansia is a Belgian-based microbiome start-up based on discoveries made by its founding scientists, Professor Willem M. de Vos, from Wageningen University, The Netherlands and Professor Patrice D. Cani, from the University of Louvain (UCL), Belgium. Isolated in 2004 at Wageningen University, A. muciniphila is one of the most abundant species found in the gut microbiota, the population of microorganisms housed in the gastrointestinal tract.
A. muciniphila is located in a particular niche: the mucus layer covering the intestinal epithelium. This location allows this bacterium to establish a close cross-talk with the host. Thanks to these interactions with the host immune and metabolic functions, A. muciniphila acts as a key gatekeeper to the intestinal barrier.