A-Mansia

Founded in 2016, A-Mansia is a Belgian-based microbiome start-up based on discoveries made by its founding scientists, Professor Willem M. de Vos, from Wageningen University, The Netherlands and Professor Patrice D. Cani, from the University of Louvain (UCL), Belgium. Isolated in 2004 at Wageningen University, A. muciniphila is one of the most abundant species found in the gut microbiota, the population of microorganisms housed in the gastrointestinal tract.

A. muciniphila is located in a particular niche: the mucus layer covering the intestinal epithelium. This location allows this bacterium to establish a close cross-talk with the host. Thanks to these interactions with the host immune and metabolic functions, A. muciniphila acts as a key gatekeeper to the intestinal barrier.

 

Key to maintain health and immunity

More than ten years of collaborative research have led to the demonstration that daily administration of live A. muciniphila can improve metabolic disorders and inflammatory conditions in mice fed with a high-fat diet. Pasteurised A. muciniphila exhibited the same, or greater, beneficial effects and completely prevented the development of disorders induced by a high-fat diet in the preclinical model.

Based on A.muciniphila, a proprietary nutritional supplement will be developed. This supplement could then be key to maintaining health and immunity, normal glycaemia, normal blood cholesterol levels and avoiding excessive weight gain.

Akkermansia muciniphila is a unique symbiont with an intimate relationship with humans. Based on A. muciniphila a nutritional supplement can be developed, which will be able to contribute to people’s quality of life.
Investment since
September 10, 2018
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